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Aralen is a medication primarily used to prevent and treat malaria. It is also prescribed for the treatment of certain autoimmune conditions such as lupus erythematosus. This medication belongs to a class of drugs known as antimalarials.

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Aralen Information

Aralen Medication Information Leaflet

Common Use

Aralen is commonly used to treat and prevent malaria. It may also be prescribed for the treatment of certain autoimmune conditions such as rheumatoid arthritis and systemic lupus erythematosus.

Generic Ingredient

The generic compound for Aralen is chloroquine phosphate.


Aralen belongs to the class of medications known as antimalarials. It is also classified as an aminoquinoline.

Clinical Use

In clinical settings, Aralen is primarily used for the treatment and prevention of malaria, particularly caused by Plasmodium falciparum and Plasmodium vivax.

Spectrum Of Activity

Aralen has a broad spectrum of activity against various species of malarial parasites. It is also known to possess some immunomodulatory effects in the treatment of autoimmune conditions.

Drug interaction

Aralen may interact with certain medications such as digoxin, cyclosporine, and mefloquine. It is important to inform the healthcare provider about all the medications being taken to avoid potential interactions.

Dosage and Directions

The dosage of Aralen varies based on the condition being treated and the individual's response. It is crucial to follow the healthcare provider's instructions regarding the dosage and administration of the medication.

Contraindications and Precautions

Aralen is contraindicated in individuals with known hypersensitivity to chloroquine phosphate or other 4-aminoquinoline compounds. Precautions should be exercised in patients with hepatic disease, alcoholism, and epilepsy.

Possible side effect

Some possible side effects of Aralen include nausea, vomiting, headache, and vision changes. It is important to seek medical attention if any adverse reactions occur.

Missed dose and Overdose

If a dose of Aralen is missed, it should be taken as soon as remembered. In case of an overdose, immediate medical assistance should be sought.

Special Cases

Special consideration should be given when administering Aralen to pediatric and geriatric populations, as well as individuals with a history of cardiac arrhythmias or glucose-6-phosphate dehydrogenase (G6PD) deficiency.

Known Non-standard Use

Aralen has been studied for its potential use in the treatment of certain viral infections, although its efficacy in these conditions is not well-established.

Patient Considerations

Patients taking Aralen should be advised to undergo regular ophthalmic examinations, especially with prolonged use, to monitor for any ocular toxicity associated with the medication.

Possible Risks

The use of Aralen may be associated with the risk of retinopathy, hemolysis in G6PD-deficient individuals, and exacerbation of psoriasis. Healthcare providers should be vigilant about these potential risks.

Breastfeeding and Pregnancy

Aralen use during pregnancy and lactation should be carefully considered based on the potential benefits and risks. Consultation with a healthcare provider is essential in such cases.

Known Alternatives

Alternatives to Aralen for the treatment of malaria and autoimmune conditions include medications such as hydroxychloroquine, mefloquine, and atovaquone-proguanil.


Aralen should be stored at room temperature, away from moisture and heat. It is important to keep the medication out of the reach of children.

Aralen FAQ

What is Aralen used for?

Aralen, also known as chloroquine, is primarily used to prevent and treat malaria. It may also be used to treat certain autoimmune conditions such as rheumatoid arthritis and lupus.

How should I take Aralen?

Aralen should be taken exactly as prescribed by your doctor. It is typically taken with a meal to prevent stomach upset. Do not take more or less than the prescribed dose and do not skip doses. Follow your doctor's instructions carefully.

What are the possible side effects of Aralen?

The common side effects of Aralen include nausea, vomiting, stomach pain, loss of appetite, diarrhea, or headache. It may also cause more serious side effects such as vision changes, muscle weakness, irregular heartbeats, or mood changes. Consult your doctor if you experience any concerning side effects.

Can I take Aralen during pregnancy?

The use of Aralen during pregnancy should be carefully considered. It may be prescribed if the benefits outweigh the risks, especially in the treatment of malaria. However, it is essential to consult with your doctor before taking Aralen if you are pregnant or planning to become pregnant.

What should I avoid while taking Aralen?

While taking Aralen, it is important to avoid consuming alcohol as it can increase the risk of certain side effects. Additionally, exercise caution when exposing your skin to sunlight as Aralen can make you more sensitive to UV light.

Can Aralen be given to children?

Aralen can be prescribed to children, but the dosage will be based on their weight. It is important to strictly follow the pediatrician's instructions for the correct dosage and duration of treatment for children.

What should I discuss with my healthcare provider before taking Aralen?

Before taking Aralen, inform your doctor about any medical conditions you have, any medications you are currently taking (especially other antimalarial drugs), and any allergies you may have. It is crucial to provide a comprehensive medical history to ensure the safe use of Aralen.

How quickly does Aralen start working?

In the case of treating malaria, Aralen typically starts working within 2 to 3 days. However, the complete course of treatment should be finished as prescribed, even if symptoms improve sooner.

Can I take Aralen with other medications?

Aralen can interact with various medications, including blood thinners, seizure medications, and certain antibiotics. It is important to consult with your doctor or pharmacist regarding potential drug interactions before taking Aralen with other medications.

Is Aralen the same as hydroxychloroquine?

Aralen and hydroxychloroquine are related medications, both belonging to the class of drugs called antimalarials. While they have some similarities, they also have differences in their uses and side effect profiles. It is essential to use each medication only as prescribed by your healthcare provider.

What should I do if I miss a dose of Aralen?

If you miss a dose of Aralen, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How long can I take Aralen?

The duration of Aralen treatment depends on the condition being treated. For malaria prevention, it may be taken long term, while for other conditions, the duration will be determined by your doctor. Do not stop taking Aralen without consulting your healthcare provider.

Is Aralen habit-forming?

Aralen is not known to be habit-forming. It is essential to take it as prescribed and not to exceed the prescribed dosage. If you have concerns about dependence on medications, discuss them with your doctor.

How does Aralen work in the body?

Aralen works by interfering with the growth of parasites in the red blood cells and has anti-inflammatory effects. In autoimmune conditions, it helps to reduce inflammation and manage symptoms such as joint pain and swelling.

Can Aralen cause vision problems?

Prolonged use of Aralen may lead to vision changes, including blurred vision or difficulty focusing. It is crucial to have regular eye examinations while taking Aralen, especially for long-term use.

Aralen Properties

  • Clinical use: Treatment and prevention of malaria
  • Spectrum of activity: Plasmodium species
  • Mechanism of action: Prevents heme polymerization
  • Classification: Aminoquinoline antimalarial
  • Recommended Dosage: 500 mg once weekly for prophylaxis; 1,000 mg followed by 500 mg after 6-8 hours then 500 mg daily for 2 days for treatment
  • Basic Side Effects: Headache, Pruritus, Nausea
  • Serious Side Effects: Retinopathy, Cardiomyopathy

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