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Sustiva, also known as efavirenz, is an antiretroviral medication used to treat HIV infection. It works by decreasing the amount of HIV in the blood, helping to boost the immune system. It is often used in combination with other HIV medications.

  • Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
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Sustiva Information

Sustiva Medication Information Leaflet

Common Use

Sustiva is commonly used to treat HIV infection. It is often prescribed in combination with other antiretroviral medications.

Generic Ingredient



Sustiva belongs to the class of medications known as non-nucleoside reverse transcriptase inhibitors (NNRTIs).

Clinical Use

Sustiva is used to control the progression of HIV infection and improve the immune system function.

Spectrum Of Activity

Sustiva is active against HIV-1, the most common strain of the virus responsible for HIV infection.

Drug interaction

Sustiva may interact with a wide range of medications. It's important to inform your healthcare provider about all the medications, supplements, and herbal products you are taking before starting Sustiva.

Dosage and Directions

The typical dose of Sustiva for adults is 600 mg once daily. It is taken orally on an empty stomach, preferably at bedtime. The dosage may vary based on individual patient factors.

Contraindications and Precautions

Sustiva is contraindicated in patients with known hypersensitivity to efavirenz or any component of the formulation. It should be used with caution in patients with a history of psychiatric disorders.

Possible side effect

Common side effects of Sustiva may include dizziness, trouble sleeping, drowsiness, and rash. More serious side effects can occur and should be reported to a healthcare provider.

Missed dose and Overdose

If a dose of Sustiva is missed, it should be taken as soon as possible unless it is almost time for the next dose. In the case of an overdose, immediate medical attention is necessary.

Special Cases

Special caution is needed when using Sustiva in patients with a history of liver disease or hepatitis B or C co-infection. Close monitoring is essential in these cases.

Known Non-standard Use

Sustiva has been studied for potential use in the treatment of other viral infections, although it is not approved for these uses.

Patient Considerations

Patients should be advised to take Sustiva exactly as prescribed and not to adjust the dose or discontinue the medication without consulting a healthcare provider.

Possible Risks

Sustiva may cause an increase in certain liver enzymes, and there is a risk of developing a serious condition called lactic acidosis. Regular monitoring is important to detect these potential risks.

Breastfeeding and Pregnancy

Sustiva should be used with caution during pregnancy. It may pass into breast milk, so breastfeeding is not recommended while taking this medication.

Known Alternatives

There are alternative medications available for the treatment of HIV infection. Your healthcare provider can discuss other options if Sustiva is not suitable for you.


Sustiva should be stored at room temperature, away from light and moisture. Keep it out of the reach of children.

Sustiva FAQ

What is Sustiva used for?

Sustiva, also known as Efavirenz, is used to treat HIV infection. It is typically used in combination with other antiretroviral medications to control the infection.

How should I take Sustiva?

Sustiva should be taken exactly as prescribed by a healthcare provider. It is usually taken on an empty stomach at bedtime to reduce the risk of side effects such as dizziness and drowsiness.

What are the common side effects of Sustiva?

Common side effects of Sustiva may include dizziness, trouble sleeping, drowsiness, trouble concentrating, and rash. It's important to discuss any concerning side effects with a healthcare provider.

Can I drink alcohol while taking Sustiva?

It is generally recommended to avoid alcohol while taking Sustiva as it may increase the risk of certain side effects such as drowsiness or dizziness.

Is Sustiva safe to take during pregnancy?

Sustiva may cause harm to an unborn baby if taken during pregnancy. It's important for women to discuss their pregnancy status with their healthcare provider before starting Sustiva.

What should I do if I miss a dose of Sustiva?

If a dose of Sustiva is missed, it should be taken as soon as remembered. However, if it is almost time for the next dose, the missed dose should be skipped and the regular dosing schedule should be resumed.

Is Sustiva addictive?

Sustiva is not addictive as it does not cause a euphoric high or cravings typically associated with addictive substances.

Can Sustiva interact with other medications?

Yes, Sustiva can interact with a wide range of other medications. It's crucial to inform the healthcare provider about all medications, including over-the-counter and herbal supplements, before starting Sustiva.

How long does it take for Sustiva to start working?

Sustiva starts working as soon as it is absorbed into the body, but it may take several weeks to months for the medication to reduce the amount of HIV in the blood to undetectable levels.

What should I tell my doctor before starting Sustiva?

Before starting Sustiva, it's important to inform the doctor about any medical conditions, ongoing treatments, allergies, or if planning for pregnancy or breastfeeding.

Can I drive while taking Sustiva?

Sustiva may cause dizziness and impair the ability to concentrate. It's recommended to assess individual response to the medication before operating a vehicle or heavy machinery.

How long do I need to take Sustiva?

The duration of Sustiva treatment depends on the individual's response to the medication and the overall HIV treatment plan laid out by the healthcare provider.

What diet should I follow while taking Sustiva?

There are no specific dietary restrictions when taking Sustiva. However, maintaining a balanced and nutritious diet is important for overall health while living with HIV.

Can I take herbal supplements with Sustiva?

It's essential to consult a healthcare provider before taking any herbal supplements with Sustiva as they may interact with the medication and affect its effectiveness.

Is Sustiva a cure for HIV?

Sustiva is not a cure for HIV. It is an antiretroviral medication that helps in controlling the virus and preventing its progression to AIDS.

Sustiva Properties

  • Clinical use: Antiretroviral therapy
  • Spectrum of activity: HIV-1
  • Mechanism of action: Non-nucleoside reverse transcriptase inhibitor (NNRTI) that impedes HIV viral RNA-dependent DNA polymerase
  • Classification: Non-nucleoside reverse transcriptase inhibitor
  • Recommended Dosage: 600 mg orally once daily, often in combination with other antiretrovirals
  • Basic Side Effects: Rash, Dizziness, Insomnia
  • Serious Side Effects: Psychiatric symptoms, Severe skin reactions, Hepatotoxicity

Sustiva Drug Class

Sustiva Other/Alternative Names


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