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Epivir is an antiviral medication used to treat HIV infection and hepatitis B. It works by slowing the growth of the virus, helping to improve the immune system.

  • Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
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Epivir Information

Epivir Medication Information Leaflet

Common Use

Epivir is commonly used to treat HIV infection and chronic hepatitis B virus infection.

Generic Ingredient

The generic compound of Epivir is called lamivudine.


Epivir belongs to the class of medications known as nucleoside reverse transcriptase inhibitors (NRTIs).

Clinical Use

Epivir is used in the clinical management of HIV-1 infection and chronic hepatitis B virus infection.

Spectrum Of Activity

Epivir has demonstrated activity against HIV-1 and hepatitis B virus, inhibiting viral replication.

Drug interaction

Epivir may interact with certain medications, including trimethoprim/sulfamethoxazole, and may require dosage adjustments or close monitoring.

Dosage and Directions

The recommended dosage of Epivir for adults and adolescents weighing at least 30 kg for the treatment of HIV-1 infection is 300 mg once daily. The dosage for the treatment of chronic hepatitis B infection may differ.

Contraindications and Precautions

Epivir is contraindicated in patients with a known hypersensitivity to lamivudine. It should be used with caution in patients with renal impairment and in those with hepatitis B virus infection.

Possible side effect

Common side effects of Epivir may include headache, nausea, fatigue, and skin rash. Other side effects may also occur and should be reported to a healthcare professional.

Missed dose and Overdose

If a dose of Epivir is missed, it should be taken as soon as possible, unless it is almost time for the next dose. If an overdose is suspected, medical attention should be sought immediately.

Special Cases

Special caution is required when administering Epivir to patients with a history of pancreatitis, as serious and potentially fatal cases have been reported.

Known Non-standard Use

Epivir may be used in non-standard regimens for the management of HIV infection. Such use should be carefully monitored by a healthcare professional.

Patient Considerations

Patients should be educated about the appropriate use and potential side effects of Epivir. Compliance with the prescribed dosage and regular monitoring are essential for treatment success.

Possible Risks

There is a potential risk of developing lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, while using Epivir. This risk may be increased in patients with pre-existing liver disease.

Breastfeeding and Pregnancy

Pregnant individuals considering the use of Epivir should discuss the potential risks and benefits with their healthcare provider. Epivir may be used during breastfeeding, but caution is advised.

Known Alternatives

There are alternative medications available for the treatment of HIV-1 infection and chronic hepatitis B virus infection. Healthcare professionals can provide information about these alternatives based on individual patient factors.


Epivir should be stored at room temperature, away from moisture and heat. It should be kept out of reach of children.

Epivir FAQ

What is Epivir used for?

Epivir, also known as lamivudine, is used to treat HIV infection. It helps to decrease the amount of HIV in the body so the immune system can work better.

What are the possible side effects of Epivir?

Common side effects of Epivir may include headache, tiredness, nausea, diarrhea, and changes in body fat distribution. It is important to consult a healthcare professional for a complete list of side effects.

How should Epivir be taken?

Epivir should be taken exactly as prescribed by a healthcare professional. It is usually taken once or twice daily with or without food. It is important not to miss any doses and to take it at the same time each day.

What should I do if I miss a dose of Epivir?

If a dose of Epivir is missed, it should be taken as soon as remembered. However, if it is almost time for the next dose, the missed dose should be skipped and the regular dosing schedule resumed. It is important not to take a double dose to make up for a missed one.

Can Epivir be taken during pregnancy?

Pregnant individuals should consult their healthcare professional before taking Epivir. It may be used during pregnancy if the potential benefits outweigh the potential risks. However, it is important to discuss this with a healthcare professional.

Is it safe to breastfeed while taking Epivir?

Epivir may pass into breast milk, and its effects on a nursing infant are not fully known. Healthcare professionals should be consulted before breastfeeding while taking this medication.

Can Epivir be used in children?

Epivir may be used in children, but the dosage is based on their weight. It is important to follow the healthcare professional's instructions for the correct dosage.

Are there any medications that should not be taken with Epivir?

It is important to inform the healthcare professional about all other medications being taken, including prescription, over-the-counter, and herbal products. Some medications may interact with Epivir, so it is crucial to seek professional advice.

How long does it take for Epivir to work?

Epivir starts working as soon as it is absorbed by the body. However, the full effects may take several weeks to months. It is important to continue taking the medication as prescribed, even if feeling well.

Can Epivir cure HIV?

Epivir helps to control HIV infection, but it does not cure it. It is important to continue taking all prescribed medications for HIV, including Epivir, to keep the virus under control.

Is it necessary to have regular blood tests while taking Epivir?

Regular blood tests are often necessary while taking Epivir to monitor the condition and ensure the medication is working effectively. The frequency of the tests will be determined by the healthcare professional.

Can Epivir cause liver damage?

In rare cases, Epivir may cause severe liver problems. It is important to be aware of the signs of liver damage, such as yellowing of the skin or eyes, dark urine, or persistent nausea/vomiting, and seek medical attention if these occur.

Is it safe to drink alcohol while taking Epivir?

Drinking alcohol should be discussed with a healthcare professional while taking Epivir. Alcohol can affect the liver, and since Epivir may also affect the liver, it is important to seek professional advice.

What is the difference between Epivir and other HIV medications?

Epivir is a type of medication called a nucleoside reverse transcriptase inhibitor (NRTI). It works by slowing the growth of the virus. Other HIV medications work in different ways, and the choice of medication depends on various factors, including the individual's condition and medical history.

Can Epivir be used for pre-exposure prophylaxis (PrEP)?

Currently, Epivir is not approved for use as pre-exposure prophylaxis (PrEP) to prevent HIV infection. There are other medications specifically approved for this purpose, and individuals should consult healthcare professionals for more information.

Epivir Properties

  • Clinical use: Antiretroviral and antiviral therapy
  • Spectrum of activity: HIV
  • Mechanism of action: Nucleoside reverse transcriptase inhibitor (NRTI) that incorporates into viral DNA by viral reverse transcriptase, causing chain termination
  • Classification: Nucleoside reverse transcriptase inhibitor
  • Recommended Dosage: 150-300 mg orally once daily or in divided doses
  • Basic Side Effects: Fatigue, Cough, Nausea
  • Serious Side Effects: Lactic acidosis, Liver enlargement, Pancreatitis

Epivir Other/Alternative Names


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